Breaking carbon-hydrogen (C-H) bonds to alter existing molecules to create new ones is an increasingly important avenue for drug development. Of particular interest is mirror-image or "one-handed" compounds, but C-H breaking ...
Materials Science
Oct 23, 2014
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A relatively simple combination of naturally occurring sugars and amino acids offers a plausible route to the building blocks of life, according to a paper published in Nature Chemistry co-authored by a professor at the University ...
Biochemistry
Aug 9, 2011
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Chirality of molecules is a crucial consideration in drug development as the enantiomeric purity of a compound can significantly impact its pharmacological properties. Chiral molecules possess mirror-image enantiomers that ...
Analytical Chemistry
Jun 6, 2023
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Homochirality is a fundamental feature of all living organism. It is well known that a pair of enantiomers of chiral drug molecules, whose structures have a non-superimposable mirror-image relationship to each other, will ...
Materials Science
Jun 30, 2020
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The concept of chirality can be challenging for the layperson, with "chemical handedness" seeming a very minor distinction. However, as the consequences of the notorious thalidomide disaster illustrate, understanding chiral ...
Analytical Chemistry
Jul 31, 2019
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Prof. Liu Bo and colleagues at the University of Science and Technology of China (USTC) have developed a chiral separation membrane capable of capturing left-handed chiral molecules and releasing the right-handed counterpart ...
Materials Science
Jun 25, 2019
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Professor Takashi Ooi and his team of researchers from Nagoya University, Japan, have designed a catalyst that performs two tasks during the course of the reaction.
Materials Science
Jan 25, 2018
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Chemists at Nagoya Institute of Technology have developed an innovative chemical reaction system, which could have applications for developing starter molecules for additional synthetic procedures in organic chemistry, as ...
Materials Science
Jul 5, 2017
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In science's equivalent of ascending Mt. Everest, researchers are reporting success in one of the most difficult challenges in synthetic chemistry—a field in which scientists reproduce natural and other substances from ...
Biochemistry
Dec 12, 2012
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Cyanide exposure can be lethal, but with careful handling, the molecule can be a very useful chemical building block. For example, from cyanide chemists can make life-essential amino acids that are in great demand as food ...
Materials Science
Oct 10, 2012
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