Enantioselective synthesis of indole derivatives

Indoles, and structures derived from them, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[ b ] indoles—frameworks made of three rings that are ...

Researchers develop catalyst with chirality at the zinc center

Researchers have designed and built a new chemical tool inspired by natural metal-containing enzymes in living organisms. The product, a tetrahedral "chiral zinc," maintains its shape for years, providing a new structure ...

Researchers access both enantiomers by varying reaction time

Homochirality is a fundamental feature of all living organism. It is well known that a pair of enantiomers of chiral drug molecules, whose structures have a non-superimposable mirror-image relationship to each other, will ...

Using corkscrew lasers to separate chiral molecules

Many of the molecular building blocks of life have two versions that are mirror images of one another, known as enantiomers. Although seemingly identical, the two enantiomers can have completely different chemical behaviour—a ...

Observing changes in the chirality of molecules in real time

Some molecules can exist in two mirror-image forms, similar to our hands. Although such so-called enantiomers have almost identical physical properties, they are not the same. The fact that they behave to each other like ...

New membrane efficiently separates mirrored molecules

Prof. Liu Bo and colleagues at the University of Science and Technology of China (USTC) have developed a chiral separation membrane capable of capturing left-handed chiral molecules and releasing the right-handed counterpart ...

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