Researchers reveal unexpected genome-wide off-target mutations caused by cytosine base editing
Chinese scientists have found that cytosine base editors (BE3 and HF1-BE3) induce genome wide off-target mutations.
Chinese scientists have found that cytosine base editors (BE3 and HF1-BE3) induce genome wide off-target mutations.
Biotechnology
Feb 28, 2019
0
101
Preprint servers—online sites that post scientific manuscripts for free, prior to peer review—are well-established in fields such as physics and biology. More recently, two chemistry preprint servers, ChemRxiv and ChemRN, ...
Other
Jan 23, 2019
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4
William Langland likely wouldn't know what to make of the latest way people are reading his poetry. In part, that's because Langland died in 1386. But it's also because his most famous work, Piers Plowman, is the subject ...
Archaeology
Jan 15, 2019
0
64
On December 29, 2008, staff scientist Sheri Sangji was working on a chemical synthesis in a lab at the University of California, Los Angeles, when one of the reagents ignited. Sangji's clothes caught fire, causing injuries ...
Other
Jan 9, 2019
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4
Uncertainty continues to swirl around scientist He Jiankui's gene editing experiment in China. Using CRISPR technology, He modified a gene related to immune function in human embryos and transferred the embryos to their mother's ...
Biotechnology
Dec 3, 2018
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20
Creating and modifying a virtual reality environment just got a lot easier thanks to software being released today by Imverse, an EPFL spin-off. The secret behind Imverse's program, which works much like a photo editor, is ...
Software
Oct 17, 2018
0
11
Apple and Facebook have figured out how to keep us glued to their devices and platforms. But they haven't figured out how to curb the misinformation that plagued them during the 2016 election and have struggled to regain ...
Internet
Jul 4, 2018
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4
Hate speech is on the rise. In Canada alone, it increased by a staggering 600 per cent between 2015 and 2016 as part of what some have called "the Trump effect."
Social Sciences
Jul 3, 2018
21
5
One of the world's early computer software editors, developed by the University of Adelaide and still in use today, is being released by the University for free use by developers around the world.
Computer Sciences
Mar 14, 2018
1
21
The news media group Newsweek was in turmoil this week amid the firing of its top editorial staff, reportedly for investigating the finances of their own company.
Internet
Feb 6, 2018
0
9