Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
0
8
The spongelike structure of metal-organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. Now, researchers reporting in ACS Applied Bio Materials have treated a chromium-containing ...
Bio & Medicine
Jan 26, 2024
0
61
Treating complex diseases such as skin cancer often requires simultaneous administration of multiple anticancer drugs. The delivery of such life-saving therapeutic drugs has evolved with the rise of nanotechnology-based drug ...
Bio & Medicine
Jan 24, 2024
0
68
A team from the University of Münster has introduced a strategy for converting carbon–nitrogen atom pairs in a frequently used ring-shaped compound into carbon–carbon atom pairs. The method has potential in the quest ...
Biochemistry
Jan 18, 2024
0
36
Global fungal infections, which affect 1 billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability. Patients undergoing chemotherapy ...
Evolution
Jan 12, 2024
0
66
For the first time, researchers have analyzed the impact of antibiotic use on the rise of treatment-resistant bacteria over the last 20 years in the UK and Norway. They show that while the increase in drug use has amplified ...
Cell & Microbiology
Jan 11, 2024
0
46
A research group at Nagoya University in Japan has developed a new catalyst that promises to revolutionize the asymmetric synthesis of pharmaceuticals called chiral macrocyclic dilithium(I) salt. It overcomes the lack of ...
Analytical Chemistry
Jan 11, 2024
0
1
MYC is the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering hope for a new era of treatments.
Biochemistry
Jan 11, 2024
0
468
In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now ...
Analytical Chemistry
Jan 10, 2024
0
100
Modern pharmaceutical research generates large amounts of data faster than ever before. To analyze and evaluate this data, it is collected and structured in extensive databases and thus provides the basis for the development ...
Cell & Microbiology
Jan 9, 2024
0
38
