Mature sperm lack intact mitochondrial DNA, study finds

New research provides insight about the bedrock scientific principle that mitochondrial DNA—the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body—is exclusively passed ...

New statistics methods for dose finding studies

Less than 0.02 per cent of potential active ingredients pass clinical tests and become commercially viable. However, it is possible that some candidates are rejected without good reason, suspects mathematician Prof Dr Holger ...

Machine learning models for drug discovery

IBM today announced that its scientists have been granted a patent on machine learning models to predict therapeutic indications and side effects from various drug information sources. IBM Research has implemented a cognitive ...

Researchers make breakthrough in fatal cat disease

A new clinical trial has resulted in a critical veterinary breakthrough - cats with feline infectious peritonitis (FIP) in remission following treatment with a novel antiviral drug. This fatal viral disease previously had ...

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