Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or "subway map" of key metabolic activities of the bacterium that causes Lyme disease. Using this map, they have successfully ...
Cell & Microbiology
Oct 19, 2023
0
8
One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided ...
Biotechnology
Oct 17, 2023
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85
Researchers from the University of Arizona Cancer Center have identified a new method of activating specific molecules to target cancer cells while leaving healthy cells unharmed.
Biochemistry
Sep 25, 2023
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2
Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers ...
Analytical Chemistry
Sep 22, 2023
0
18
Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers.
Molecular & Computational biology
Aug 1, 2023
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30
Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate ...
Cell & Microbiology
Jul 28, 2023
0
5
Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...
Biochemistry
Jun 7, 2023
0
40
Development of vaccines against SARS-CoV-2 has been rapid, but the rise of variants forces scientists to frequently modify treatments. Ideally, therapies would target mutation-resistant viral proteins, but this has proven ...
Biochemistry
Apr 26, 2023
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44
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
0
36
Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap ...
Analytical Chemistry
Mar 28, 2023
0
34
