A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs – five years in the making – provides important clues about how the role of timing may influence the way drugs work ...
Biotechnology
Oct 27, 2014
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Ludwig Maximilian University of Munich researchers report that a new class of chemical compounds makes cancer cells more sensitive to chemotherapeutic drugs. They have also pinpointed the relevant target enzyme, thus identifying ...
Biochemistry
Sep 30, 2014
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Proteins are chains of amino acids that, when folded into certain structural patterns and also when unfolded, exert functions within cells. Proteins receive signals that are transmitted from one to the next and that are essential ...
Cell & Microbiology
Jun 12, 2014
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Restricting calorie consumption is one of the few proven ways to combat aging. Though the underlying mechanism is unknown, calorie restriction has been shown to prolong lifespan in yeast, worms, flies, monkeys, and, in some ...
Cell & Microbiology
Jan 2, 2014
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Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine ...
Biotechnology
Nov 27, 2013
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Diamonds are sometimes considered as a girl's best friend. Now, this expression is about to have a new meaning. Indeed, nanometric scale diamond particles could offer a new way to detect cancer far earlier than previously ...
Bio & Medicine
Oct 23, 2013
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A tiny but unexpected change to a segment of RNA in a single-cell organism looks a lot like a mistake, but is instead a change to the genetic information that is essential to the organism's survival.
Cell & Microbiology
Oct 3, 2013
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Candida albicans is a double agent: In most of us, it lives peacefully, but for people whose immune systems are compromised by HIV or other severe illnesses, it is frequently deadly. Now a new study from Johns Hopkins and ...
Biochemistry
Sep 24, 2013
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To stay ahead in the race against drug-resistant infections, scientists constantly search for and exploit vulnerabilities in deadly bacteria. Now, researchers from Brown and the Massachusetts Institute of Technology have ...
Biochemistry
Sep 18, 2013
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Researchers have identified five enzymes that are essential to the survival of a parasitic worm that infects livestock worldwide and is a great threat to global food security. Two of these proteins are already being studied ...
Biotechnology
Aug 28, 2013
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