RNA modification could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell, which sheds new light on the complex process underlying RNA transcription.
Cell & Microbiology
Jul 12, 2024
0
3
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability ...
Analytical Chemistry
Apr 8, 2024
0
43
Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats.
Cell & Microbiology
Apr 8, 2024
0
48
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
0
31
Cornell researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes ...
Biochemistry
Oct 18, 2023
0
231
Click chemistry could help to synthesize a variety of molecules quickly and reliably by piecing together small units. In particular, it emphasizes the development of new combinatorial chemistry methods based on the synthesis ...
Analytical Chemistry
Jul 13, 2023
0
9
A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions.
Biochemistry
Jun 8, 2023
0
8
For a long time, antibiotics were considered a silver bullet against bacterial infections. Over time, many pathogens have adapted to resist antibiotics, so the search for new drugs is becoming increasingly important. An international ...
Cell & Microbiology
Oct 11, 2022
0
60
Scientists at EPFL have found a way to synthesize large numbers of macrocyclic compounds, which are needed for developing drugs against difficult disease targets.
Biochemistry
Jul 12, 2022
0
28
The chemical industry has only scratched the surface of possible molecules that could be used as drugs, which is unimaginably greater than the number of stars in the universe. To make navigating this vast chemical space more ...
Other
Jun 30, 2022
0
12
