Shining some light on an obscure proteome

Mass-spectrometry based proteomics is the big-data science of proteins that allows the monitoring of the abundance of thousands of proteins in a sample at once. Therefore, it is a particularly well-suited readout for discovering ...

Mapping the effects of mutations in antibiotic-resistant bacteria

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic ...

Researchers devise sex-cell precursors with staying power

Human primordial germ cells (PGCs) are the early precursors of the eggs (oocytes) and sperm that are necessary to keep humankind alive and reproducing. Medical researchers attempt to study their function and development using ...

New point spread functions developed for particle 3D tracking

Nanoparticle positioning and tracking have a wide range of uses in life science, drug research and development. Real-time recording of the intracellular and extracellular motion of nano particles is of great significance ...

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