A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
Cell membranes are barriers that maintain cellular homeostasis, and the intracellular delivery of biologically functional molecules, including peptides, proteins, and nucleic acids to manipulate cellular functions. Conventional ...
Bio & Medicine
Mar 6, 2023
0
62
In a recent study, researchers from the Department of Organic Chemistry (OC) and Materials Research Centre (MRC), Indian Institute of Science (IISc), show that surface modifications of two-dimensional molybdenum disulfide ...
Bio & Medicine
Mar 2, 2023
0
43
New antitubercular drugs are vital due to the spread of resistant strains of Mycobacterium tuberculosis. A research team from Skoltech, MIPT, and the Institute of Bioorganic Chemistry of the National Academy of Sciences of ...
Biochemistry
Feb 28, 2023
0
5
Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance. The researchers made slight changes to a small molecule to reduce its metabolism and ...
Biochemistry
Feb 28, 2023
0
73
A recent study published in the journal Science China Life Sciences was led by Dr. Nan Qiao (Laboratory of Health Intelligence, Huawei Cloud Computing Technologies), Dr. Hualiang Jiang (Shanghai Institute of Materia Medica, ...
Analytical Chemistry
Feb 24, 2023
0
8
Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of Spanish National Research Council (CSIC) have developed a series of photosensitive molecule drugs that can be reversibly activated by external light, ...
Biochemistry
Feb 16, 2023
0
60
Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.
Biochemistry
Feb 8, 2023
0
65
Two catalysts working in tandem enable inexpensive formate salts to perform difficult dearomative reactions, resulting in products potentially useful for drug development.
Materials Science
Feb 7, 2023
0
19
In the cell, messenger RNAs—or mRNAs—are translated into proteins and eventually degraded, but the relationship between translation and mRNA decay remains cloudy. FMI researchers developed an innovative tool to control ...
Cell & Microbiology
Feb 6, 2023
0
5
