Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...
Cell & Microbiology
Dec 8, 2022
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56
In recent years, research and development on quantum computers has made considerable progress. Quantum chemical calculations for electronic structures of atoms and molecules are attracting great attention as one of the most ...
Analytical Chemistry
Nov 29, 2022
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158
The world's aging population, the growing burden of chronic and infectious diseases, and the emergence of novel pathogens have made the need for new treatments more urgent than ever. Yet, discovering a new drug and bringing ...
Biochemistry
Nov 16, 2022
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40
Researchers at UC Riverside are paving the way for diabetes and cancer patients to forget needles and injections, and instead take pills to manage their conditions.
Biochemistry
Nov 10, 2022
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162
It's a paradox: Life needs water to survive, but a world full of water can't generate the biomolecules that would have been essential for early life. Or so researchers thought.
Evolution
Nov 3, 2022
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3
NUS chemists have developed an effective method to access enantioenriched drug-like compounds through multicomponent olefin cross-coupling using chiral nickel-based catalysts.
Materials Science
Oct 28, 2022
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44
Making complex polymers with precisely controlled structures is much simpler thanks to a new one-pot, one-step synthesis procedure.
Polymers
Oct 25, 2022
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21
Molecular crystals—the building blocks that make up many drugs and other products—sometimes take on water molecules, which can alter the crystals in unforeseen ways. Notably, predicting which crystals are likely to contain ...
Biochemistry
Oct 24, 2022
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26
The Cambridge Crystallographic Data Center (CCDC) today highlights that a search of the Cambridge Structural Database (CSD) has found nearly 1,800 conglomerate crystal structures—molecules that have spontaneously enriched ...
Biochemistry
Oct 6, 2022
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20
An important component of the vaccines protecting people against SARS-CoV-2 virus and its variants are lipid nanoparticles, or LNPs. These circular particles carry therapeutic mRNA payloads, the snippets of genetic material ...
Bio & Medicine
Sep 23, 2022
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