In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such ...
Biochemistry
May 15, 2023
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48
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his Ph.D. research, chemist Xuequan Zhou brought that goal a little closer. ...
Bio & Medicine
May 12, 2023
0
113
Research in the International Journal of Computational Biology and Drug Design, has looked at the potential of various bioflavonoids as inhibitors of the SARS-CoV-2 virus, which causes COVID-19. The compounds—narirutin, ...
Biochemistry
May 4, 2023
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6
A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications. Instead of targeting the bacteria directly, the drug blocks key toxins involved in the ...
Cell & Microbiology
Apr 18, 2023
1
67
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
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38
If you know the atoms that compose a particular molecule or solid material, the interactions between those atoms can be determined computationally, by solving quantum mechanical equations—at least, if the molecule is small ...
Quantum Physics
Apr 7, 2023
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125
Think about how frustrating it is to try to fit a gift into a box that is too small. Sometimes you just need a bigger box.
Bio & Medicine
Apr 6, 2023
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89
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
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36
Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, ...
Biochemistry
Mar 23, 2023
0
26
Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...
Cell & Microbiology
Mar 13, 2023
0
3
