Oral peptides: A new era in drug development

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...

Compact accelerator technology achieves major energy milestone

Particle accelerators hold great potential for semiconductor applications, medical imaging and therapy, and research in materials, energy and medicine. But conventional accelerators require plenty of elbow room—kilometers—making ...

A better trigger for targeted drug delivery

Biomolecular 'nanocarriers' formed by the careful assembly of protein subunits are common in nature and perform a range of essential roles in biological processes, powered by the biological energy carrier adenosine-5'-triphosphate ...

Sensing small molecules may revolutionize drug design

Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task ...

Deep learning predicts drug-drug and drug-food interactions

Drug interactions, including drug-drug interactions (DDIs) and drug-food constituent interactions (DFIs), can trigger unexpected pharmacological effects, including adverse drug events (ADEs), with causal mechanisms often ...

Edible fungus foils dangerous grapefruit-drug interactions

Scientists in Florida report that adding an edible mushroom-like fungus to grapefruit juice may help to reduce the serious side effects that can occur when people taking certain prescription drugs drink grapefruit juice. ...

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