Proteins are like tiny machines in our bodies, helping with almost everything we do, including breaking down food, carrying messages between cells, and building and repairing tissues, like muscles and skin.
Molecular & Computational biology
May 16, 2024
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1
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit ...
Biochemistry
May 8, 2024
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13
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open ...
Biochemistry
May 6, 2024
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27
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature ...
Biochemistry
Apr 24, 2024
1
37
Researchers have created scaffolds with enhanced strength by fabricating 20 vol% polydopamine-modified nano hydroxyapatite (pDA-nHA), featuring a distinctive lamellar structure. These scaffolds were then immersed in a polyetherketoneketone ...
Polymers
Apr 22, 2024
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19
Inspired by what human liver enzymes can do, Scripps Research chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions ...
Analytical Chemistry
Apr 19, 2024
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49
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability ...
Analytical Chemistry
Apr 8, 2024
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43
The active ingredient in many drugs is what's known as a small molecule: bigger than water, much smaller than an antibody and mainly made of carbon. It's tough, however, to make these molecules if they require a quaternary ...
Materials Science
Apr 6, 2024
4
81
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent ...
Molecular & Computational biology
Apr 4, 2024
0
16
Droplet microfluidics has revolutionized single-cell analysis, crucial for genomics, drug discovery, and diagnostics, by partitioning samples into nanoliter droplets for detailed cellular analysis. Yet, its broader adoption ...
Cell & Microbiology
Apr 1, 2024
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