Stop and go: How the cell deals with transcriptional roadblocks

Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...

DNA biosynthesis discovery could lead to better antibiotics

Combating several human pathogens, including some biological warfare agents, may one day become a bit easier thanks to research reported by a University of Iowa chemist and his colleagues in the April 16 issue of the journal ...

'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' ...

Highly efficient, low-cost method developed to reduce DNA errors

DNA only persists through replication—naturally or synthetically. While humans need the genetic material to be reproduced in order to replace old or damaged cells, the ability to replicate DNA in a laboratory setting can ...

page 5 from 7