DNA is like the computer code of the body, and it must be preserved for our bodies to survive. Yet, as cells grow and change, DNA is vulnerable to defects, especially double strand breaks (DSBs). In fact, DSBs regularly occur ...
Cell & Microbiology
Jan 16, 2018
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4
PhD student Willem Noteborn has investigated supramolecular structures. These can be useful for the loading of medicines and signalling molecules regarding, for example, cellular differentiation. In his thesis, he describes ...
Polymers
Dec 11, 2017
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32
Transcription—the reading of a segment of DNA into an RNA template for protein synthesis—is fundamental for nearly all cellular processes, including growth, responding to stimuli, and reproduction. Now, Whitehead Institute ...
Cell & Microbiology
Dec 8, 2017
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32
When James Michael Creeth finished adding acid to the sample of DNA taken from a calf's thymus gland, he wasn't just completing the experiments that would earn him his PhD. He was paving the way for a discovery that would ...
Biotechnology
Nov 14, 2017
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4
Researchers from Aalto University and Helsinki University have reported a strategy that significantly increases the stability of DNA nanostructures against DNA digesting enzymes, enhances delivery rates and, most importantly, ...
Biochemistry
Oct 6, 2017
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11
DNA is the stuff of life, but it is also the stuff of nanotechnology. Because molecules of DNA with complementary chemical structures recognize and bind to one another, strands of DNA can fit together like Lego blocks to ...
Bio & Medicine
Sep 4, 2017
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24
High-resolution crystal structure reveals a new pathway for RNA during a nontraditional form of transcription—the process by which RNA is produced from a DNA template. Caught during the act of reiterative transcription, ...
Cell & Microbiology
Aug 22, 2017
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6
One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.
Biochemistry
Aug 2, 2017
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138
A research group of Tokyo University of Agriculture and Technology, Tokyo Institute of Technology, Keio University and Tohoku University have successfully developed an artificial cytoskeletal structure for cell models (liposomes ...
Cell & Microbiology
Jun 26, 2017
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2
A research group led by Hitoshi Kurumizaka, a professor of structural biology at Waseda University, unveiled the crystal structure of an overlapping dinucleosome, a newly discovered chromatin structural unit. This may explain ...
Biotechnology
Apr 13, 2017
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