For several years, researchers have been trying to use computational methods for exact string matching, which entails identifying repeating patterns in long strings of text or digits. This is because tools that can automatically ...
(Phys.org) -- A team of researchers in the US has successfully encoded a 5.27 megabit book using DNA microchips, and they then read the book using DNA sequencing. Their experiments show that DNA could be used for long-term ...
A new paper published today (April 24) in the journal Nature by an international team of 279 scientists led by the Royal Botanic Gardens, Kew presents the most up-to-date understanding of the flowering plant tree of life.
Plants & Animals
Apr 24, 2024
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147
Leveraging gamers and video game technology can dramatically boost scientific research, according to a new study published today in Nature Biotechnology.
Cell & Microbiology
Apr 15, 2024
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378
Pushing into a new chapter of technologically advanced biological sensors, scientists from the University of California San Diego and their colleagues in Australia have engineered bacteria that can detect the presence of ...
Biotechnology
Aug 10, 2023
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98
Over the past 100 million years, mammals have adapted to nearly every environment on Earth. Scientists with the Zoonomia Project have been cataloging the diversity in mammalian genomes by comparing DNA sequences from 240 ...
Evolution
Apr 27, 2023
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581
The sled dog Balto has been celebrated in books and movies for his role in delivering desperately needed diphtheria antitoxin to Nome, Alaska, in 1925. Now, his DNA has enabled scientists to explore the genetics of 1920s ...
Evolution
Apr 27, 2023
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3816
Our bodies' genes work together to regulate how our cells behave. For example, if you skin your knee, your genes use a chemical messaging system to direct an army of cells to heal the abrasion. If scientists could create ...
Biochemistry
Aug 19, 2022
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513
A simple statistical test shows that contrary to current practice, the "gaps" within DNA protein and sequence alignments commonly used in evolutionary biology can provide important information about nucleotide and amino acid ...
Evolution
Aug 16, 2022
3
591
A research team led by the Technical University of Munich (TUM) has succeeded for the first time in producing a molecular electric motor using the DNA origami method. The tiny machine made of genetic material self-assembles ...
Bio & Medicine
Jul 21, 2022
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738
A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.
The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."
Sequences can be derived from the biological raw material through a process called DNA sequencing.
In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:
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