DNA repair protein caught in act of molecular theft

Scientists have observed, for the first time, an intermediate stage in the chemical process that repairs DNA methylation damage and regulates many important biological functions that impact health conditions such as obesity, ...

Developing tools to visualize DNA repair as never before

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...

Neutral evolution shapes lifespan and aging

Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans ...

The secret to safe DNA repair

Michael Hendzel knows all too well that there is little that people can do to control the stability of their genetic code. But he hopes his latest research will help impact this elusive and crucial aspect of medicine. Published ...

Key protein aids in DNA repair

Scientists have shown in multiple contexts that DNA damage over our lifetimes is a key mechanism behind the development of cancer and other age-related diseases. Not everyone gets these diseases, because the body has multiple ...

High fidelity: Researcher finds keys to genome integrity

Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of our genetic code. However, in the course of replicating, our DNA frequently runs into roadblocks, arising ...

The right way to repair DNA

Is it better to do a task quickly and make mistakes, or to do it slowly but perfectly? When it comes to deciding how to fix breaks in DNA, cells face the same choice between two major repair pathways. The decision matters, ...

page 9 from 27