GUIDE-Seq technology might detect double-strand DNA breaks in plants
Double-stranded breaks in DNA can be detected with several technologies. Doing so in plants is exceptionally difficult, but GUIDE-Seq shows promise in new studies.
Double-stranded breaks in DNA can be detected with several technologies. Doing so in plants is exceptionally difficult, but GUIDE-Seq shows promise in new studies.
Biotechnology
Sep 22, 2016
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256
(Phys.org) —From bacteria to plants to humans, all organisms have mechanisms that they use to repair DNA damaged by ultraviolet (UV) light. This fundamental maintenance function is critical to our health because damaged ...
Biotechnology
Jan 24, 2014
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Defects in DNA can cause serious harm to an organism, including cell death or the development of cancer. Efficient repair mechanisms are therefore of vital importance. LMU chemist Professor Christian Ochsenfeld, Chair of ...
Cell & Microbiology
Aug 6, 2015
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23
In the early 1990s, Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry at Caltech, discovered an unexpected property of DNA—that it can act like an electrical wire to transfer electrons quickly ...
Biochemistry
Feb 24, 2017
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96
An organism's genome could be compared to a complex system of instructions that allows it not only to develop, but also to carry out all the activities essential to its survival. To do this, this genome needs to be expressed ...
Molecular & Computational biology
Dec 3, 2021
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158
Natural selection has produced mammals that age at dramatically different rates. Take, for example, naked mole rats and mice; the former can live up to 41 years, nearly ten times as long as similar-size rodents such as mice.
Cell & Microbiology
May 31, 2022
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73
Biologists and informaticists at Indiana University have produced one of the most extensive pictures ever of mutation processes in the DNA sequence of an organism, elucidating important new evolutionary information about ...
Biotechnology
Sep 17, 2012
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DNA, which stores genetic information in the majority of organisms on Earth, is not easily destroyed. It readily absorbs ultraviolet (UV) radiation, but finds ways to recover.
Nanomaterials
Dec 8, 2015
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947
An enzyme crucial to the process of DNA repair in our cells has been mapped in atomic detail by researchers at the University of Dundee, the UK's top-rated University for Biological Sciences.
Cell & Microbiology
Dec 11, 2015
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56
Scientists have observed, for the first time, an intermediate stage in the chemical process that repairs DNA methylation damage and regulates many important biological functions that impact health conditions such as obesity, ...
Biochemistry
Nov 10, 2010
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