Scientists have taken pictures of the BRCA2 protein for the first time, showing how it works to repair damaged DNA.
Cell & Microbiology
Oct 5, 2014
1
0
Important new information on one of the most critical protein machines in living cells has been reported by a team of researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and ...
Biochemistry
Jan 11, 2012
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0
Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism. Now, researchers from Japan have identified mechanisms that choose between alternate pathways of DNA repair to ...
Evolution
Apr 30, 2020
0
17
A groundbreaking and surprising discovery provides a major conceptual change of what is most important to cells: the fidelity of the DNA transcription process - accurately copying the DNA message into RNA, the precursor to ...
Cell & Microbiology
Oct 4, 2017
0
12
Several drugs now being used to treat heart failure and atrial arrhythmia also show promise as DNA disruptors in cancer cells and could be readily repurposed as anticancer agents, according to a new study by Yale researchers.
Biochemistry
Mar 14, 2016
0
36
One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.
Biochemistry
Aug 2, 2017
0
138
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Biotechnology
Sep 17, 2023
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1
Scientists at the University of Liverpool, in partnership with The Genome Analysis Centre, Norwich, have generated the first whole-genome sequencing data of the naked mole-rat, a rodent that is resistant to cancer and lives ...
Biotechnology
Jul 5, 2011
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0
One of the biggest helpers in our bodies' ongoing efforts to prevent DNA mutations—mutations that can lead to cancer—is actually rather tiny. Electrons, as it turns out, can signal proteins that repair DNA to patch up ...
Biochemistry
Jun 18, 2018
0
54
How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university ...
Molecular & Computational biology
Sep 1, 2021
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