CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.
Biotechnology
Aug 17, 2016
0
172
Scientists at The Scripps Research Institute (TSRI) have engineered a bacterium whose genetic material includes an added pair of DNA "letters," or bases, not found in nature. The cells of this unique bacterium can replicate ...
Biochemistry
May 7, 2014
10
0
From a bat's wings to an elephant's cancer resistance, an interdisciplinary team of scientists at University of Utah Health are using animals' unique traits to pinpoint regions of the human genome that might affect health. ...
Biotechnology
Mar 6, 2018
0
241
Although the genome editing system known as CRISPR/Cas has revolutionized genetic research in cell lines, its overall efficiency has been relatively poor when used to generate genetically altered animals for disease modeling. ...
Biotechnology
Mar 24, 2015
0
24
New biological research reveals how an invading virus hijacks a cell's workings by imitating a signaling marker to defeat the body's defenses. By manipulating cell signals, the virus destroys a defensive protein designed ...
Cell & Microbiology
Mar 26, 2012
0
0
Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific ...
Optics & Photonics
Mar 14, 2013
5
0
A new technology can read the order (sequence) of the "letters" making up DNA code with enough accuracy to reveal how bacteria use high-speed evolution to defeat antibiotics. That is the finding of a study led by researchers ...
Biotechnology
Jun 22, 2016
0
536
Much about tiny, swimming rotifers makes them ideal study subjects. Although barely visible to the naked eye, these transparent animals and their innards are readily viewed under a microscope. What's more, they grow readily ...
Biotechnology
Aug 4, 2023
0
376
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...
Molecular & Computational biology
May 21, 2019
0
171
If the ultraviolet radiation from the sun damages human DNA to cause health problems, does UV radiation also damage plant DNA? The answer is yes, but because plants can't come in from the sun or slather on sunblock, they ...
Cell & Microbiology
Apr 17, 2018
0
322
