Bringing better grapes a step closer to reality

Grapes are one of the world's most economically important fruit crops, but the woody perennial takes three years to go from seed to fruit, and that makes traditional breeding expensive and time-consuming.

Mechanism for hMTH1's broad substrate specificity revealed

Human MutT homolog 1 (hMTH1) protein acts as the primary enzyme for breaking down (hydrolyzing) damaged (oxidized) deoxynucleoside triphosphates (dNTPs) the substrates of DNA synthesis. Recently, hMTH1 has drawn attention ...

How TFIIH uses XPG to located damaged DNA

Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.

Uncovering the mystery of DNA replication

By looking into the mechanism of a backward enzyme, scientists speculate why DNA replication always happens in the forward direction.

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