Dutch researchers have developed a new tool to label DNA for studying chromosomes in live cells. The tool is non-invasive and can be applied in culture but also in living organisms, such as zebrafish embryos. The team published ...
Cell & Microbiology
Nov 4, 2021
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27
As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe. Determining the identity of DNA and RNA molecules has now become commonplace ...
Bio & Medicine
Oct 21, 2021
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80
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cell membranes. This allows for selectivity and also reversibility—the binding can also be undone. ...
Cell & Microbiology
Sep 2, 2021
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46
Being able to detect DNA from a single cell is important for the detection of diseases and genetic disorders. Measuring single DNA molecules has been possible for some time; however, directly detecting samples at the point ...
Bio & Medicine
Aug 24, 2021
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281
A trio of researchers working at the School of Life Sciences, Tsinghua-Peking Center for Life Sciences, has chemically synthesized a mirror-image of Pfu DNA polymerase. In their paper published in the journal Nature Biotechnology, ...
Polymers are long, chain-like molecules which are everywhere in biology. DNA and RNA are polymers formed by many consecutive copies of nucleotides coupled together. When being transported within or between cells, these biological ...
Nanophysics
Jun 29, 2021
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18
While DNA is often idealized as the "molecule of life," it is also a highly sophisticated polymer that can be used for next-generation materials. Beyond the fact that it can store information, further fascinating aspects ...
Biochemistry
May 28, 2021
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32
Most drugs are small. But large molecules could be enormously useful medicines—if we could only get them inside our cells. Now, a group of researchers in biomedical engineering—a shared department with the UConn School ...
Biotechnology
May 17, 2021
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13
Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program," a process that controls when and in what order segments ...
Molecular & Computational biology
Apr 23, 2021
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1241
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization ...
Cell & Microbiology
Apr 15, 2021
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59
