In human chromosomes, DNA is coated by proteins to form an exceedingly long beaded string. This "string" is folded into numerous loops, which are believed to help cells control gene expression and facilitate DNA repair, among ...
Cell & Microbiology
Apr 14, 2022
0
275
A new imaging technique has allowed researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and the University of Pittsburgh to see how DNA loops around a protein that aids in the ...
Cell & Microbiology
Feb 11, 2016
0
1233
In spore-forming bacteria, chromosomal locations of genes can couple the DNA replication cycle to critical, once-in-a-lifetime decisions about whether to reproduce or form spores. The new finding by Rice University bioengineers ...
Cell & Microbiology
Jul 9, 2015
8
784
A research team based in Houston's Texas Medical Center has found that the proteins that turn genes on by forming loops in human chromosomes work like the sliding plastic adjusters on a grade-schooler's backpack. This discovery ...
Biotechnology
Oct 19, 2015
2
1040
Recently, Professor Chunxiang You from Shandong Agricultural University and her colleagues published a review article titled "Regulation of fleshy fruit ripening: from transcription factors to epigenetic modifications" in ...
Molecular & Computational biology
Aug 8, 2022
0
22
The entire genomic material of a cell must be packed into a tiny cell nucleus in such a way, that on the one hand, it can be stored in an organized manner and, on the other hand, it can be transcribed, duplicated or repaired ...
Molecular & Computational biology
May 20, 2022
1
235
A multi-institutional team spanning Baylor College of Medicine, Rice University, Stanford University and the Broad Institute of MIT and Harvard has created the first high-resolution 4-D map of genome folding, tracking an ...
Biotechnology
Oct 6, 2017
0
363
Researchers report that a single-stranded DNA-binding protein (SSB), once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth along single-stranded DNA, gradually allowing ...
Biochemistry
Oct 21, 2009
0
1
(PhysOrg.com) -- Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many ...
General Physics
Mar 16, 2009
0
0
Have a close-up look at DNA; you'll see it wiggles in the oddest way. Put more scientifically, a piece of DNA's movements are often counterintuitive to those of objects in our everyday grasp. Take a rod of rubber, for example. ...
General Physics
Apr 20, 2016
0
183
