'Undruggable' cancer protein becomes druggable, thanks to shrub
A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.
A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.
Biochemistry
Apr 20, 2021
1
2674
The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed.
Cell & Microbiology
Jul 3, 2015
72
5312
From a bat's wings to an elephant's cancer resistance, an interdisciplinary team of scientists at University of Utah Health are using animals' unique traits to pinpoint regions of the human genome that might affect health. ...
Biotechnology
Mar 6, 2018
0
241
The DNA molecule is chemically unstable, giving rise to DNA lesions of various kinds. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. The DNA damage response ...
Cell & Microbiology
Mar 31, 2015
1
1773
A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus—a finding ...
Cell & Microbiology
Sep 2, 2022
0
163
An international team of scientists has sequenced the genome of a capuchin monkey for the first time, uncovering new genetic clues about the evolution of their long lifespan and large brains.
Biotechnology
Feb 15, 2021
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1882
Scientists at the Francis Crick Institute have made a surprising discovery about the Vaccinia virus, a large DNA virus belonging to the pox family that was used as the vaccine to eradicate smallpox.
Cell & Microbiology
May 3, 2017
0
197
Researchers have determined a new feature of how the natural ends of our chromosomes are protected from harmful outcomes.
Cell & Microbiology
Aug 17, 2023
0
164
New research has revealed the function of a widely shared enzyme component, the Zf-GRF domain, as a critical molecular tool necessary for manipulating DNA during repair processes.
Cell & Microbiology
Jan 7, 2017
0
26
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
0
9