DNA double-strand breaks are one of the biggest threats to the genome and a driving force of carcinogenesis. Cellular repair mechanisms such as homologous recombination are essential for the maintenance of genome stability ...
Cell & Microbiology
Aug 24, 2022
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10
The genetic information we receive from our parents in the form of chromosomes are mosaics assembled from the two copies of chromosomes each parent has. How such cuts—or breaks—in our genetic material are repaired is ...
Cell & Microbiology
Apr 7, 2016
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4
To understand why some cancer cells resist radiotherapy, an international team of researchers has used crystallography to "photograph" the first moments of the molecular ballet that allows these cells to repair their DNA. ...
Molecular & Computational biology
Oct 9, 2018
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7
