All your movies on a single DVD: study

Scientists unveiled new DVD technology on Wednesday that stores data in five dimensions, making it possible to pack more than 2,000 movies onto a single disc.

Milky Way's warp caused by galactic collision, Gaia suggests

Astronomers have pondered for years why our galaxy, the Milky Way, is warped. Data from ESA's star-mapping satellite Gaia suggest the distortion might be caused by an ongoing collision with another, smaller, galaxy, which ...

The rare molecule weighing in on the birth of planets

Astronomers using one of the most advanced radio telescopes have discovered a rare molecule in the dust and gas disc around a young star—and it may provide an answer to one of the conundrums facing astronomers.

Massive brown dwarf detected by astronomers

An international team of astronomers has found a new brown dwarf, one of the most massive objects of this type discovered to date. The newly detected brown dwarf, designated EPIC 212036875 b, turns out to be about 50 times ...

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DLG4

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene.

PSD-95 is a member of the membrane-associated guanylate kinase (MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.

PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels.

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