Scientists have now reported evidence of the true conditions in Hell, perhaps because no one has ever returned to tell the tale. Hell has been imagined as a supremely uncomfortable place, hot and hostile to bodily forms of ...
Astronomy
Feb 20, 2024
6
61
Black holes are like temperamental toddlers. They spill food all the time, but ESA's XMM-Newton has caught a black hole in the act of "flipping over the table" during an otherwise civilized meal.
Astronomy
Feb 8, 2024
0
55
Intervertebral disk degeneration (IDD) is a main contributor to low back pain. Oxidative stress, which is highly associated with the progression of IDD, increases senescence of nucleus pulposus-derived mesenchymal stem cells ...
Cell & Microbiology
Aug 28, 2023
0
1
In today's world of digital information, an enormous amount of data is exchanged and stored on a daily basis.
Nanomaterials
Jul 25, 2023
0
28
Scientists have made a new discovery on how small planets might form. Researchers at the University of Warwick investigated the "birth environment" of planets—areas of gas and dust that swirl around a central star—known ...
Planetary Sciences
Jul 3, 2023
0
697
The mystery of a stellar flare a trillion times more powerful than the largest of solar flares may have been solved by a team of scientists who believe a massive young planet is burning up in a superheated soup of raw material ...
Astronomy
Jun 12, 2023
0
26
Imperial College researchers have created a spinning disk of plasma in a lab, mimicking disks found around black holes and forming stars.
Plasma Physics
May 15, 2023
1
1705
A study led by Monash University astronomers published new near-infrared images of the system HD 169142, which enabled the confirmation of a protoplanet forming in the system.
Astronomy
Apr 5, 2023
0
20
Little 'hurricanes' that form in the disks of gas and dust around young stars can be used to study certain aspects of planet formation, even for smaller planets which orbit their star at large distances and are out of reach ...
Astronomy
Jan 6, 2023
0
186
Examining the spines of Neandertals, an extinct human relative, may explain back-related ailments experienced by humans today, a team of anthropologists has concluded in a new comparative study.
Evolution
Mar 3, 2022
1
657
PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene.
PSD-95 is a member of the membrane-associated guanylate kinase (MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels.
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