Time-lapse imaging can make complicated processes easier to grasp—think of a stitched-together sequence of photos that chronicles the construction of a building. Now, scientists from the Department of Energy's Lawrence ...
Cell & Microbiology
Sep 2, 2015
3
62
Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules. RNA-binding proteins such as RC3H1 (also known ...
Cell & Microbiology
Jul 31, 2015
0
27
By studying the yeast used in beer- and bread-making, researchers at the University of Pittsburgh School of Medicine have uncovered the mechanism by which ancient proteins repair DNA damage and how their dysfunction could ...
Cell & Microbiology
Jul 28, 2015
0
41
During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication ...
Biotechnology
May 4, 2015
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39
A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a ...
Cell & Microbiology
Mar 2, 2015
0
14
Sites where DNA is damaged may cause a molecule that slides along the DNA strand to scan for damage to slow on its patrol, delaying it long enough to recognize and initiate repair. The finding suggests that the delay itself ...
Biochemistry
Jan 28, 2015
0
52
Biological molecules such as proteins can contain hundreds of thousands of atoms, which makes it very difficult to understand their function in detail. Identifying the exact atomic structure of these complex molecules is ...
General Physics
Jul 18, 2014
0
0
A group of researchers from Arizona State University are part of a larger team reporting a major advance in the study of human proteins that could open up new avenues for more effective drugs of the future. The work is being ...
Analytical Chemistry
Dec 20, 2013
1
0
The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, and hints ...
Cell & Microbiology
Sep 16, 2013
0
0
A new straightforward method enables monitoring the response of nuclear proteins to DNA damage in time and space. The approach is based on nonlinear photoperturbation.
Biochemistry
Aug 9, 2013
0
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