The ability to accurately repair DNA damaged by spontaneous errors, oxidation or mutagens is crucial to the survival of cells. This repair is normally accomplished by using an identical or homologous intact sequence of DNA, ...
Cell & Microbiology
Sep 3, 2014
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Large molecular motors consisting of up to a dozen different proteins regulate access to the genome, which is essential for the transcription of genes and for the repair of DNA damage. Susan Gasser and her team now reveal ...
Cell & Microbiology
Aug 28, 2014
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Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build ...
Cell & Microbiology
Jun 29, 2014
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Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ζ (Polζ) is ...
Biochemistry
Jun 25, 2014
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(Phys.org) —Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.
Biochemistry
May 12, 2014
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Birds in the exclusion zone around Chernobyl are adapting to – and may even be benefiting from – long-term exposure to radiation, ecologists have found. The study, published in the British Ecological Society's journal ...
Ecology
Apr 28, 2014
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Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, ...
Cell & Microbiology
Apr 21, 2014
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housands of consumer products—including cosmetics, sunscreens, and clothing—contain nanoparticles added by manufacturers to improve texture, kill microbes, or enhance shelf life, among other purposes. However, several ...
Bio & Medicine
Apr 9, 2014
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A group from the University of Geneva, Switzerland, discovers a key factor that curbs the undesirable triggering of DNA replication.
Cell & Microbiology
Mar 27, 2014
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Plasma medicine is a new and rapidly developing area of medical technology. Specifically, understanding the interaction of so-called atmospheric pressure plasma jets with biological tissues could help to use them in medical ...
Plasma Physics
Mar 25, 2014
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