Switching DNA and RNA on and off

DNA and RNA are naturally polarised molecules containing electric dipole moments due to the presence of a significant number of charged atoms at neutral pH. Scientists believe that these molecules have an in-built polarity ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

Mayo researchers find off/on switch for DNA repair protein

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...

Timing is key for bacteria surviving antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth ...

Molecular brake on human cell division prevents cancer

Researchers at Karolinska Institutet, Sweden, and the University of Sussex, England, have discovered that the process of copying DNA generates a brake signal that stalls cell division. This molecular brake ensures that the ...

How does plant DNA avoid the ravages of UV radiation?

If the ultraviolet radiation from the sun damages human DNA to cause health problems, does UV radiation also damage plant DNA? The answer is yes, but because plants can't come in from the sun or slather on sunblock, they ...

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