G protein-coupled receptors (GPCRs) play a crucial role in cell signal transduction and comprise the largest drug target protein family. Despite recent breakthroughs in structural and pharmacological studies of these receptors, ...
Cell & Microbiology
Apr 20, 2022
0
65
Tetrahymena, a tiny single celled-organism, turns out to be hiding a surprising secret: it's doing respiration—using oxygen to generate cellular energy—differently from other organisms such as plants, animals or yeasts. ...
Cell & Microbiology
Mar 31, 2022
0
397
In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body's organs ...
Cell & Microbiology
Feb 25, 2022
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83
The vast majority of biological processes rely on proteins to carry out various jobs in all living cells, including neurons, which transmit information throughout the nervous system.
Cell & Microbiology
Feb 3, 2022
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36
Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or feces of Mastomys rats. Even though many people who become infected with Lassa ...
Cell & Microbiology
Dec 2, 2021
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27
The intricate functions of cellular processes have mystified scientists for decades. But with the help of tools like cryogenic electron microscopy (Cryo-EM), researchers at Penn State College of Medicine are starting to see ...
Biotechnology
Dec 1, 2021
0
108
The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and ...
Cell & Microbiology
Nov 29, 2021
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98
University of Colorado Anschutz Medical Campus researchers have observed how an RNA molecule from a virus forms a complex, three-dimensional structure, and is able to change its shape to hijack host proteins. The details ...
Cell & Microbiology
Nov 19, 2021
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90
When scientists needed to visualize the structure of the spike protein, which coronaviruses use to infiltrate human cells, they turned to cryo-electron microscopy. One of the most powerful imaging tools in a researcher's ...
General Physics
Sep 21, 2021
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24
Most of the cells in our bodies—be they bone, muscle or pancreas cells—are locked into the right place with the help of tiny anchors (called 'focal adhesions'). These strong anchors use protein chains to link the cell ...
Cell & Microbiology
Sep 13, 2021
0
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