Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications, new research has found.
Molecular & Computational biology
May 15, 2024
0
57
Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry ...
Biochemistry
Aug 28, 2023
0
48
Researchers at the University of Wisconsin–Madison have described the way an enzyme and proteins interact to maintain the protective caps, called telomeres, at the end of chromosomes, a new insight into how a human cell ...
Cell & Microbiology
Aug 1, 2022
0
192
In 2017, Salk scientists reported that tilting a frozen protein sample as it sat under an electron microscope was an effective approach to acquiring better information about its structure and helping researchers understand ...
Biotechnology
Oct 4, 2019
0
31
In basic biology, medical sciences and pharmaceutical sciences, structural analyses of membrane proteins are important, and single-particle analysis by cryoEM is now very powerful method. Japanese researchers have developed ...
Biotechnology
Oct 3, 2019
0
14
With ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
Evolution
Jul 11, 2019
0
0
Work that previously could have taken chemists months can now be done in minutes.
Analytical Chemistry
Nov 7, 2018
0
40
In November 2017, a Titan Krios cryo-electron microscope (cryo-EM) was inaugurated at the ESRF, the European Synchrotron, France. Data collected on this cryo-EM features in a Nature publication describing the activation cycle ...
Biochemistry
Oct 31, 2018
0
22
Ancient microbes that thrive in some of the world's most extreme environments and modern-day humans have more in common than meets the eye—namely, they both respire and conserve energy using a similar molecular mechanism, ...
Biochemistry
May 10, 2018
0
23
A revolutionary technique dubbed cryo-electron microscopy, which has peered closer at the Zika virus and an Alzheimer's enzyme, earned scientists Jacques Dubochet, Joachim Frank and Richard Henderson the Nobel Chemistry ...
Other
Oct 4, 2017
1
1245
