Spotting a molecular warhead for disease in the human gut
Yale scientists are using new chemical tools to identify and understand molecules in the human gut that alter DNA and regulate inflammatory bowel diseases and colorectal cancers.
Yale scientists are using new chemical tools to identify and understand molecules in the human gut that alter DNA and regulate inflammatory bowel diseases and colorectal cancers.
Biochemistry
Apr 7, 2015
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24
A nanosized polymer, developed by a research team from Ben-Gurion University of the Negev, can selectively deliver chemotherapeutic drugs to blood vessels that feed tumors and metastases and has emerged as an effective treatment ...
Bio & Medicine
Apr 8, 2024
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72
Early screening can mean the difference between life and death in a cancer and disease diagnosis. That's why University of Central Florida researchers are working to develop a new screening technique that's more than 300 ...
Bio & Medicine
Mar 25, 2021
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57
Antibody treatments may be able to activate the immune system to fight diseases like Parkinson's, Alzheimer's and colorectal cancer, but they are less effective when they bind with themselves and other molecules that aren't ...
Biotechnology
Sep 11, 2023
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23
Cancers cells use a special technique to propagate: They delete their "programmed death" gene through mutation, and seemingly "forget" to die when their lifetime is over, and continue to grow instead. A research team from ...
Biochemistry
Jun 11, 2020
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6
Phosphatases of regenerating liver (PRLs) are a family of enigmatic proteins involved in cell growth and metabolism present in various species. From humans to fruit flies, they play a unique role in the growth of cancerous ...
Biochemistry
May 15, 2023
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4
The bacteria residing in your digestive tract, or your gut microbiota, may play an important role in your ability to respond to chemotherapy drugs in the clinic, according to a new study by scientists at the University of ...
Cell & Microbiology
Apr 24, 2017
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9
Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like ...
Bio & Medicine
Dec 12, 2023
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9
Researchers have analyzed the three-dimensional structure of a protein that suppresses the development of colorectal polyposis, MUTYH, at the atomic level and clarified the repair mechanism for DNA mispairings by MUTYH. Since ...
Biotechnology
Aug 2, 2021
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82
A research team led by Prof. Zhao Guoping from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has proposed a mechanism by which protein disulfide isomerase (PDI) can translocate ...
Cell & Microbiology
Oct 17, 2022
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