Characterized drugs show unexpected effects

When Alexander Flemming discovered a mold on a culture plate overgrown with bacteria in 1928, he did not expect to find one of the most widely used active substances: penicillin. Accidental discoveries and the identification ...

Graphene material strengthens nerve signaling in the brain

Less than 20 years after it was developed, a thin, resilient sheet of carbon atoms with remarkable properties known as graphene is transforming biomedical fields as far flung as tissue engineering, neuroprosthetics and drug ...

Possible new route to fight dengue virus pointed

Researchers have identified enzymes and biochemical compounds called lipids that are targeted and modified by the dengue virus during infection, suggesting a potential new approach to control the aggressive mosquito-borne ...

Researchers identify structure of apolipoprotein

Using a sophisticated technique of x-ray crystallography, researchers Xiaohu Mei, PhD, and David Atkinson, PhD, from Boston University School of Medicine (BUSM) have for the first time obtained an "image" of the structure ...

'Fatostatin' is a turnoff for fat genes

A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell ...

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