Small heat-shock proteins (sHSPs) are molecular chaperones that bind to unfolded proteins to prevent protein aggregation and defend against cellular stress. Mutations in human sHSPs are associated with inherited diseases ...
Biochemistry
Oct 17, 2018
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6
Researchers from the Verstreken lab (VIB-KU Leuven) have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, ...
Cell & Microbiology
Sep 7, 2018
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2
Proteins play a crucial role in the human body. These complex molecules help maintain the structure and function of organs and tissue, regulating cellular activity at the most fundamental level.
Biochemistry
Apr 27, 2018
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4
Chaperones are a set of proteins that are specialised to assist proteins in the human body. They help proteins to fold to the right shape and protect them from adapting wrong shapes. The research group of Alireza Mashaghi, ...
Biochemistry
Apr 19, 2018
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8
Researchers from the Center for Molecular Biology of Heidelberg University (ZMBH) and the German Cancer Research Center (DKFZ) have investigated the mode of action of a molecular chaperone vital to protein synthesis. Together ...
Cell & Microbiology
Sep 8, 2017
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2
Proteins fulfill vital functions in our body. They transport substances, combat pathogens, and function as catalysts. In order for these processes to function reliably, proteins must adopt a defined three-dimensional structure. ...
Cell & Microbiology
Aug 25, 2016
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3
Three researchers whose work with cell proteins has implications for Alzheimer's disease, cancer and other degenerative illnesses will share one of the largest awards in medicine and science in the U.S., officials at a New ...
Other
Aug 3, 2016
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5
Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Biochemistry
Feb 14, 2014
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0
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins. ...
Cell & Microbiology
Jan 18, 2013
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0
The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the ...
Biochemistry
Oct 9, 2012
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