For decades, molecular biologists studying a class of molecular chaperones known as heat shock proteins (Hsp70s) have relied on the Hsp70s found in bacteria as the model system. Now one of the world's experts on the molecule ...
Biochemistry
Nov 9, 2018
0
54
Mitochondria are cell organelles that play critical roles in maintaining the cell's health, or homeostasis. One way that mitochondria do this is by harvesting energy though oxidative phosphorylation, where various enzymes ...
Cell & Microbiology
Nov 2, 2017
0
10
On October 26th Nature will publish a study that overturns the decades-old textbook model of action for a protein that is central for many processes in living cells. Researchers at the FOM Institute AMOLF and the University ...
Cell & Microbiology
Oct 26, 2016
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20
In proper society of yesterday, the chaperone insured that couples maintained proper courting rituals. In biology, a group of proteins called chaperonins makes sure that proteins are folded properly to carry out their assigned ...
Cell & Microbiology
Jan 20, 2010
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0
Researchers from the Verstreken lab (VIB-KU Leuven) have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, ...
Cell & Microbiology
Sep 7, 2018
0
2
A team of researchers at the University of Massachusetts Amherst has announced a major new advance in understanding how our genetic information eventually translates into functional proteins—one of the building blocks of ...
Molecular & Computational biology
Oct 12, 2021
0
120
Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Biochemistry
Feb 14, 2014
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0
Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists ...
Biochemistry
Dec 6, 2012
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1
Proteins are the workhorses of the cell and thus responsible for almost all biological functions including metabolism, signal transmission or the determination of the cell's shape. However, before they can fulfill their various ...
Cell & Microbiology
May 9, 2014
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0
The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the ...
Biochemistry
Oct 9, 2012
0
0
