Dark centers of chromosomes reveal ancient DNA

Geneticists exploring the dark heart of the human genome have discovered big chunks of Neanderthal and other ancient DNA. The results open new ways to study both how chromosomes behave during cell division and how they have ...

Research signals arrival of a complete human genome

It's been nearly two decades since a UC Santa Cruz research team announced that they had assembled and posted the first human genome sequence on the internet. Despite the passage of time, enormous gaps remain in our genomic ...

Reading the dark heart of chromosomes

Although the genomes of thousands of plant and animal species have been sequenced, for most of these genomes a significant portion is missing—the highly repetitive DNA. In the midst of these mysterious genome compartments ...

New insights into centromere structure

Researchers led by Osaka University used cryogenic electron microscopy to analyze the atomic structure of the centromeric region of the chromosome, essential for cell division. A protein called CENP-A marks the centromere; ...

How chromosomes 'cheat' for the chance to get into an egg

Each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. Theoretically, when you create a gamete—a sperm or an egg—each copy has a 50-50 shot at being passed on. ...

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