Defining the centromere

The division of cells is a highly-regulated and complex process which requires the organised collaboration of a multitude of different cellular components. Although the basic principles are known, many components and their ...

Dark centers of chromosomes reveal ancient DNA

Geneticists exploring the dark heart of the human genome have discovered big chunks of Neanderthal and other ancient DNA. The results open new ways to study both how chromosomes behave during cell division and how they have ...

Reading the dark heart of chromosomes

Although the genomes of thousands of plant and animal species have been sequenced, for most of these genomes a significant portion is missing—the highly repetitive DNA. In the midst of these mysterious genome compartments ...

Study unlocks secrets of an elusive genome compartment

Although much of the human genome has been sequenced and assembled, scientists have hit roadblocks trying to map unassembled regions of DNA that consist mostly of repetitive sequences, including the centromere.

Keeping chromosomes in check: A new role for heterochromatin

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...

How yeast cells detect genetic infections

ETH researchers studying yeast cells have discovered a new mechanism for detecting foreign genetic material from pathogens or environmental contamination, and rendering it harmless.

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