Centriole instability might contribute to some cases of microcephaly

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...

Super-resolution microscopy reveals a twist inside of cells

If you want to understand the underlying mechanisms of cellular motility and division, then the centriole is the organelle of interest. Each cell has a pair of centrioles which help to segregate chromosomes during cell division. ...

A scaffold at the center of our cellular skeleton

All animal cells have an organelle called a centrosome, which is essential to the organization of their cell skeleton. The centrosome plays fundamental roles, especially during cell division, where it allows equal sharing ...

How cells learn to 'count'

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes. Trillions of mammalian cells achieve this uniformity—but some consistently ...

Progress in super-resolution microscopy

Going deeper and deeper into cells with the microscope; imaging the nucleus and other structures more and more accurately; getting the most detailed views of cellular multi-protein complexes: All of these are goals pursued ...

Super-resolution microscopy builds multicolor 3-D from 2-D

Super-resolution microscopy is a technique that allows researchers to see beyond the diffraction limit of light. The technique has garnered increasing interest, especially since its developers won the Nobel Prize in Chemistry ...

A critical inheritance from dad ensures healthy embryos

An important feature for life is what embryos receive from mom and dad upon fertilization. Oddly enough, centrioles, the structures responsible for cell division and flagella movement, are given by the paternal gamete. How ...

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