Beyond genes: Are centrioles carriers of biological information?

Centrioles are barrel-shaped structures inside cells, made up of multiple proteins. They are currently the focus of much research, since mutations in the proteins that make them up can cause a broad range of diseases, including ...

How cells learn to 'count'

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes. Trillions of mammalian cells achieve this uniformity—but some consistently ...

Super-resolution microscopy builds multicolor 3-D from 2-D

Super-resolution microscopy is a technique that allows researchers to see beyond the diffraction limit of light. The technique has garnered increasing interest, especially since its developers won the Nobel Prize in Chemistry ...

A scaffold at the center of our cellular skeleton

All animal cells have an organelle called a centrosome, which is essential to the organization of their cell skeleton. The centrosome plays fundamental roles, especially during cell division, where it allows equal sharing ...

Super-resolution microscopy reveals a twist inside of cells

If you want to understand the underlying mechanisms of cellular motility and division, then the centriole is the organelle of interest. Each cell has a pair of centrioles which help to segregate chromosomes during cell division. ...

Making cells turn cartwheels

Centrioles are barrel-shaped connection hubs that, like key Meccano parts, hold together the microtubule connection rods that form the structural framework of the cells in our bodies.

How protein suicide assure healthy cell structures

Centrioles are tiny structures in the cell that play an important role in cell division and in the assembly of cilia and flagella. Changes in the number of centrioles are involved in diseases, such as cancer or infertility. ...

Keeping centrioles in check to ensure proper cell division

(Phys.org) —The duplication of cellular contents and their distribution to two daughter cells during cell division are amongst the most fundamental features of all life on earth. How cell division occurs and is coordinated ...

Centriole instability might contribute to some cases of microcephaly

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...

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