Investigating a hospital superbug's resistance power

Treatment of severe infections caused by pathogenic bacteria relies on "last resort" antibiotics, but rising resistance by "superbugs" to most clinically approved drugs leaves patients exposed to possible fatalities.

DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

How bacteria cope with stress

When exposed to stress, bacteria allow their metabolism to take a break during which they suppress, for example, the incorporation of proteins into membranes. Scientists from Marburg, Freiburg and Munich have discovered this ...

A multidimensional view of SARS-CoV-2

What exactly happens when the corona virus SARS-CoV-2 infects a cell? In an article published in Nature, a team from the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry paints a comprehensive ...

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