New mRNA technology turns cells into long-lasting drug factories

A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan ...

A molecular pit crew responsible for refuelling in signaling cells

During IndyCar races, pit stop crews will often refuel a car, replace wheels and complete minor repairs on a race car within 10 seconds. In this short time, a dozen or so people work rapidly and in a highly coordinated manner ...

When cells sense the cue for growth

Researchers of the Genome Dynamics Project team at Tokyo Metropolitan Institute of Medical Science have revealed a new mechanism controlling cellular proliferation in response to serum, which triggers growth of resting cells.

DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

Study reveals the protein structure of the human apoptosome

Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative ...

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