Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

Manipulating stress response in cells could help slow down aging

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have found that a stress response in cells, when "switched on" at a post-reproductive age, could be the key to slow down aging and promote longevity.

DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

Light-powered microbes are super-producing chemical factories

Sharing is key to living in society, whether it's toddlers sharing toys or nations sharing natural resources; but there's no avoiding the fact that one side getting more means that the other side gets less. Now, researchers ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

How bacteria cope with stress

When exposed to stress, bacteria allow their metabolism to take a break during which they suppress, for example, the incorporation of proteins into membranes. Scientists from Marburg, Freiburg and Munich have discovered this ...

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