Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Effects of nanoplastics on Canadian and Guadeloupean oysters

Oysters' exposure to plastics is concerning, particularly because these materials can accumulate and release metals which are then absorbed by the mollusks. According to a recent study published in the journal Chemosphere, ...

How one fern can soak up so much arsenic—and not die

Arsenic-contaminated soil and groundwater pose risks to millions of Americans and hundreds of millions of people worldwide. Cleaning up the toxic metal is a laborious and expensive process, with some remediations of arsenic ...

Two studies find stress reprograms cells

In a pair of publications, researchers have shown how cells adapt to stressors—like water loss—by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send ...

New, more sensitive sensor for evaluating drug safety

A new technique for evaluating drug safety can detect stress on cells at earlier stages than conventional methods, which mostly rely on detecting cell death. The new method uses a fluorescent sensor that is turned on in a ...

How protein interactions drive cellular death

Researchers at the Universities of Tübingen and Konstanz, the Ruhr-Universität Bochum, the Max Planck Institute of Intelligent Systems in Stuttgart, and the German Cancer Research Centers have worked together to gain new ...

Study reveals the protein structure of the human apoptosome

Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative ...

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