National University of Singapore chemists have discovered that aggregated, photosensitized, gold nanoparticle conjugates can be used for multimodal imaging and synergistic phototherapy to destroy cancer cells effectively ...
Bio & Medicine
Feb 9, 2023
0
37
Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work—until now.
Biotechnology
Jan 23, 2023
0
77
Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Cell & Microbiology
Dec 8, 2022
0
71
The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed ...
Biotechnology
Nov 14, 2022
0
108
Tumor targeting is a prerequisite for effective cancer therapy because it enhances the therapeutic outcome and decreases adverse effects. However, effective targeting is challenging to achieve with nanoparticles (NPs) coated ...
Bio & Medicine
Oct 31, 2022
0
23
Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers. Scientists can build them in various shapes with different materials, often as porous, ...
Bio & Medicine
Oct 27, 2022
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55
A research team led by Prof. Zhao Guoping from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has proposed a mechanism by which protein disulfide isomerase (PDI) can translocate ...
Cell & Microbiology
Oct 17, 2022
0
6
Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.
Biochemistry
Oct 10, 2022
0
91
University of Central Florida material sciences engineers Melanie Coathup and Sudipta Seal have designed a cerium oxide nanoparticle—an artificial enzyme—that protects bones against damage from radiation. The nanoparticle ...
Bio & Medicine
Sep 26, 2022
0
154
One approach to treating cancer is photodynamic therapy using photo-uncaging systems, in which light is used to activate a cancer-fighting agent in situ at the tumor. However, suitable agents must be stable under visible ...
Biochemistry
Sep 20, 2022
0
104
