DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...
Molecular & Computational biology
Aug 10, 2022
0
14
In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...
Cell & Microbiology
Jul 19, 2022
0
47
An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how ...
Cell & Microbiology
Jul 18, 2022
0
33
A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals ...
Cell & Microbiology
Jun 20, 2022
0
278
The membrane-bound form of angiotensin converting enzyme 2 (ACE2) is essential for enabling infection with SARS-CoV-2, the virus that causes COVID-19, according to a study published in the journal Cell.
Cell & Microbiology
May 27, 2022
0
185
Healthy human cells have two (diploid) sets of chromosomes. However, it may also happens that cells have a tetraploid (quadruple) set. Usually, they do not divide further and die, but some cells can escape this fate. An international ...
Cell & Microbiology
Apr 8, 2022
0
63
When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.
Cell & Microbiology
Mar 21, 2022
0
35
Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
Molecular & Computational biology
Nov 22, 2021
0
849
Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using ...
Biotechnology
Nov 19, 2021
1
476
Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature ...
Cell & Microbiology
Oct 29, 2021
0
83
