Effective pain relief without the debilitating side effects of traditional opioids is closer to becoming a reality thanks to a study by an all-RIKEN team into the structure and dynamics of a drug-bound opioid receptor.
Biotechnology
Jul 18, 2024
0
99
A team led by Prof. Dr. Han Sun from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has elucidated an important mechanism in the function of TREK channels at an atomic level. The results, published in ...
Molecular & Computational biology
Jul 10, 2024
0
25
Scientists at the University of Cambridge have developed an atlas of proteins describing how the proteins behave inside human cells. This tool could be used to search for the origins of diseases related to proteins misbehaving, ...
Cell & Microbiology
Jul 10, 2024
0
43
Female mammals—including humans—are born with all of their egg cells. Of a woman's one to two million egg cells, about 400 mature before menopause and can be fertilized. Some egg cells therefore survive for several decades—and ...
Cell & Microbiology
Jul 9, 2024
0
32
Mayday! SOS! Distress signals like these are used around the world to indicate an emergency. The cells that make up your body also have their own versions of emergency signals. These get activated if a cell is infected by ...
Cell & Microbiology
Jul 8, 2024
0
1
Maternal messenger RNAs (mRNAs), located within the cytoplasm of an immature egg, are crucial for jump starting development. Following fertilization, these mRNAs are passed onto the zygote, the first newly formed cell.
Cell & Microbiology
Jul 5, 2024
0
22
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are "enveloped viruses," viruses that have an exterior envelope that surrounds them largely composed ...
Biochemistry
Jul 3, 2024
0
21
In a recent study, researchers at Johns Hopkins Medicine suggest that the cell's messenger RNA (mRNA)—the major translator and regulator of genetic material—along with a critical protein called ZAK—spurs the cell's ...
Cell & Microbiology
Jul 2, 2024
0
68
The social amoeba Dictyostelium discoideum is a valuable model to study the regulation of macropinocytosis. A research team led by Prof. Cai Huaqing from the Institute of Biophysics of the Chinese Academy of Sciences has ...
Cell & Microbiology
Jul 2, 2024
0
0
A recent paper by the Pilhofer Lab (IMBB) and the Matos Lab (formerly IBC, now Max Perutz Labs in Vienna), published in the journal Cell, unveils a multiscale filament identification workflow to characterize protein filaments ...
Molecular & Computational biology
Jul 1, 2024
0
1
