Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.
Biotechnology
Feb 1, 2024
0
112
New photonic tools for medical imaging can be used to understand the nonlinear behavior of laser light in human blood for theranostic applications. When light enters biological fluids it is quickly scattered, however, some ...
Mike Graham knows that fluid dynamics can reveal much about how the flow of blood helps and hinders individual blood cells as they go about their work.
Soft Matter
May 7, 2015
0
53
Big, small, broad, narrow, long or short, turned up, pug, hooked, bulbous or prominent, humans inherit their nose shape from their parents, but ultimately, the shape of someone's nose and that of their parents was formed ...
Evolution
Mar 16, 2017
1
186
Human red blood cells (RBCs) are extremely resilient and have the capacity to undergo cellular deformation as they navigate across various micro-vessels and capillaries. Over their 120-day normal lifespan, RBCs must undergo ...
Cell & Microbiology
Sep 17, 2019
0
77
Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called ...
Biotechnology
Jan 27, 2021
0
166
Best known as a pathogen that causes food poisoning or steals nutrients away from its host, the E. coli bacterium actually plays a critical role in promoting health by producing a compound that helps cells take up iron, new ...
Cell & Microbiology
Aug 23, 2018
0
109
A trio of scientists from the University of Wisconsin-Madison and the Morgridge Institute for Research participated in an international think tank this month on the intersection of genome editing technology and national security.
Biotechnology
Oct 24, 2017
0
47
Cystic fibrosis, sickle cell anemia, Huntington's disease and phenylketonuria are all examples of disorders caused by the mutation of a single nucleotide, a building block of DNA. The human DNA consists of approximately 3 ...
Biotechnology
Feb 27, 2017
0
124
CRISPR has sparked a renaissance in genome editing. Now, next-generation CRISPR technologies let scientists modify the genome more efficiently and precisely than before. Such tools could one day serve as therapeutics, but ...
Biotechnology
Jun 15, 2020
0
33
