Fungus found in humans shown to be nimble in mating game

Brown University researchers have discovered that Candida albicans, a human fungal pathogen that causes thrush and other diseases, pursues same-sex mating in addition to conventional opposite-sex mating.

How Candida albicans exploits lack of oxygen to cause disease

Scientists from Umeå university have shown that the yeast Candida albicans can modulate and adapt to low oxygen levels in different body niches to cause infection and to harm the host. Studying adaption to hypoxic or anoxic ...

RNA interference found in budding yeasts

Some budding yeast species have the ability to silence genes using RNA interference (RNAi). Until now, most researchers thought that no budding yeasts possess the RNAi pathway because Saccharomyces cerevisiae, the protoypical ...

Fatal fungal infections resist newest class of drugs

Fungi that cause severe infections in those with compromised immune systems are resisting the action of the latest group of antifungal drugs. Uncovering their strategies for doing this will lead to more effective treatments, ...

Heat shock protein drives yeast evolution

Whitehead Institute researchers have determined that heat shock protein 90 (Hsp90) can create heritable traits in brewer's yeast (Saccharomyces cerevisiae) by affecting a large portion of the yeast genome. The finding has ...

Driving drug resistance out of fungi

Candida albicans is a notorious human fungal pathogen that causes thrush and serious systemic infections. Opportunistic C. albicans fungi, which often live inconspicuously in the normal flora of human skin and gut, can switch ...

Natural compound found in plants inhibits deadly fungi

A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi—including its most virulent species, Candida auris, an emerging global health threat. The journal ACS Infectious ...

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