The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
0
136
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection ...
Biotechnology
Oct 28, 2021
0
388
Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that ...
Bio & Medicine
Mar 2, 2015
1
1549
(PhysOrg.com) -- About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT's Robert Langer for gene therapy, the insertion of genes into living ...
Bio & Medicine
Nov 6, 2009
3
0
Cell therapies for cancer can be potentially enhanced using a CRISPR RNA-editing platform, according to a new study published Feb. 21 in Cell.
Cell & Microbiology
Feb 21, 2024
0
70
Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they workâuntil now.
Biotechnology
Jan 23, 2023
0
77
The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed ...
Biotechnology
Nov 14, 2022
0
108
DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...
Molecular & Computational biology
Aug 10, 2022
0
14
Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ...
Bio & Medicine
Jan 8, 2020
0
138
To overcome the off-target mutations that commonly occur with CRISPR/Cas9 genome editing methods, researchers at Harvard Medical School and Massachusetts General Hospital have developed two strategies that greatly improve ...
Biotechnology
Jul 20, 2015
0
45
